NLRP3-IN-72
NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. NLRP3-IN-72 exhibits anti-inflammatory and antioxidant activities. NLRP3-IN-72 has an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protecting against pyroptosis, and an EC50 of 0.6 μM for inducing HO-1.
For research use only. We do not sell to patients.
- CAS No.: 3043952-13-9
- Formula: C19H20FN5O
- Molecular Weight:353.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-1β 0.3 μM (IC50) |
HO-1 0.6 μM (EC50) |
Chemical Information
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CAS No. 3043952-13-9
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Molecular Weight 353.39
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Formula C19H20FN5O
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SMILES
CN1C2=CC=C(F)C=C2N=C1NC3=NC(C=C(CN(C)CC)C=C4)=C4O3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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