304481-72-9
Chemical Structure
PKUMDL-WQ-2101
- CAS No.: 304481-72-9
- Formula:C14H11N3O6
- Molecular Weight:317.25
IUPAC Name: (E)-2,4-dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide
InChIKey: OXONIXZPWKJHMW-VIZOYTHASA-N
SMILES: O=C(C1=CC=C(C=C1O)O)N/N=C/C2=CC([N+]([O-])=O)=CC=C2O
Biological Activity: PKUMDL-WQ-2101 is a non-NAD+-competing allosteric phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 34.8 μM. PKUMDL-WQ-2101 exhibits antitumor activity[1].
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PKUMDL-WQ-2101 | 99.94% | PKUMDL-WQ-2101 is a non-NAD+-competing allosteric phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 34.8 μM. PKUMDL-WQ-2101 exhibits antitumor activity. | ||||||||||||||||||||
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Keywords