3052814-85-1
3052814-85-1
Chemical Structure
Anti-inflammatory agent 52
- CAS No.: 3052814-85-1
- Formula:C24H21ClN2O3S
- Molecular Weight:452.95
InChIKey: FUYBXRVZBAFANK-UHFFFAOYSA-N
SMILES: O=C(COC1=CC=C(C=C1)N2C(SCC2=O)C3=CC=C(C=C3)C)NC4=CC=C(C=C4)Cl
Biological Activity: Anti-inflammatory agent 52 (compound 7j) is an orally active selective COX-2 inhibitor. Anti-inflammatory agent 52 has anti-HT29 transfer activity, which leads to periodic arrest in G2/M phase. Anti-inflammatory agent 52 has safety, moderate ability to suppress inflammation. Anti-inflammatory agent 52 has a rare property of suppressing the development of tumor in mouse model, showing anti-cancer activity[1].
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Anti-inflammatory agent 52 | Anti-inflammatory agent 52 (compound 7j) is an orally active selective COX-2 inhibitor. Anti-inflammatory agent 52 has anti-HT29 transfer activity, which leads to periodic arrest in G2/M phase. Anti-inflammatory agent 52 has safety, moderate ability to suppress inflammation. Anti-inflammatory agent 52 has a rare property of suppressing the development of tumor in mouse model, showing anti-cancer activity. | |||||||||||||||||||||
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