3053753-61-7
3053753-61-7
Chemical Structure
SARS-CoV-2 PLpro-IN-1
- CAS No.: 3053753-61-7
- Formula:C18H19N5O
- Molecular Weight:321.38
InChIKey: DEUIPJITGWQDKC-CYBMUJFWSA-N
SMILES: COC1=NC=C(C=C1)C2=NC3=C(C=C2)N=CC=C3N[C@@H]4CCNC4
Biological Activity: SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent and competitive inhibitor of SARS-CoV-2 PLpro with an IC50 of 15.06 μM and a Ki of 22.93 μM. SARS-CoV-2 PLpro-IN-1 inhibits the proliferation of Vero cell with an IC50 of 7.47 μM[1].
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SARS-CoV-2 PLpro-IN-1 | SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent and competitive inhibitor of SARS-CoV-2 PLpro with an IC50 of 15.06 μM and a Ki of 22.93 μM. SARS-CoV-2 PLpro-IN-1 inhibits the proliferation of Vero cell with an IC50 of 7.47 μM. | |||||||||||||||||||||
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References
Keywords
