SARS-CoV-2 PLpro-IN-1
SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent and competitive inhibitor of SARS-CoV-2 PLpro with an IC50 of 15.06 μM and a Ki of 22.93 μM. SARS-CoV-2 PLpro-IN-1 inhibits the proliferation of Vero cell with an IC50 of 7.47 μM.
For research use only. We do not sell to patients.
- CAS No.: 3053753-61-7
- Formula: C18H19N5O
- Molecular Weight:321.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 15.06 μM (SARS-CoV-2 PLpro)
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
17 μM
Compound: 34
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Cytotoxicity against CHO cells measured after 48 hrs by MTT assay
Cytotoxicity against CHO cells measured after 48 hrs by MTT assay
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[PMID: 38918002] |
Chemical Information
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CAS No. 3053753-61-7
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Molecular Weight 321.38
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Formula C18H19N5O
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SMILES
COC1=NC=C(C=C1)C2=NC3=C(C=C2)N=CC=C3N[C@@H]4CCNC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)