3055319-82-6
3055319-82-6
Chemical Structure
VVD-699
- CAS No.: 3055319-82-6
- Formula:C25H30ClFN2O6S2
- Molecular Weight:573.10
InChIKey: YWSLDFWCZLZVST-DRZNZDJGSA-N
SMILES: COC1=CC(C2=C(Cl)C=CC=C2)=C(S(N3CC[C@](C(N[C@@H](/C=C\S(C)(=O)=O)C)=O)(F)C[C@H]3C)(=O)=O)C=C1
Biological Activity: VVD-699 is a covalent blocker of the RAS-p110α interaction with oral activity. VVD-699 inhibits activation of PI3Kα (IC50: 104 nM in H358 cells) . VVD-699 inhibits phosphorylated AKT. VVD-699 can be used for the research of KRAS mutant/amplified cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VVD-699 | 99.83% | VVD-699 is a covalent blocker of the RAS-p110α interaction with oral activity. VVD-699 inhibits activation of PI3Kα (IC50: 104 nM in H358 cells) . VVD-699 inhibits phosphorylated AKT. VVD-699 can be used for the research of KRAS mutant/amplified cancer. | ||||||||||||||||||||
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References
Keywords
