3056974-50-3
Chemical Structure
KRAS-IN-41
- CAS No.: 3056974-50-3
- Formula:C30H37FN10OS
- Molecular Weight:604.74
InChIKey: LEBZUTXUQPPUNJ-CVOJIUGNSA-N
SMILES: NC1=C([C@@H](C)N(C2=NC(N3CC4(CCC5=C4C(C#N)=C(N)S5)C3)=NC(OC[C@@]6(CCC7)N7C[C@H](F)C6)=N2)CC)C=CC=N1
Biological Activity: KRAS-IN-41 is an inhibitor of KRAS with IC50 values of <0.01 μM for KRAS G12D and KRAS G12V. KRAS-IN-41 inhibits RAS mutant cell lines, GP2D (KRAS-G12D) and SW620 (KRAS-G12V). KRAS-IN-41 can be used in cancer research[1].
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KRAS-IN-41 | KRAS-IN-41 is an inhibitor of KRAS with IC50 values of <0.01 μM for KRAS G12D and KRAS G12V. KRAS-IN-41 inhibits RAS mutant cell lines, GP2D (KRAS-G12D) and SW620 (KRAS-G12V). KRAS-IN-41 can be used in cancer research. | |||||||||||||||||||||
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Keywords