3057274-61-7
3057274-61-7
Chemical Structure
COX-2/NLRP3-IN-1
- CAS No.: 3057274-61-7
- Formula:C24H19Cl2N5OS
- Molecular Weight:496.41
InChIKey: FVRCIDOILZVWPL-UHFFFAOYSA-N
SMILES: ClC1=C(NC2=CC=CC=C2CC3=NN=C4N3N=C(C5=C(OC)C=CC=C5)CS4)C(Cl)=CC=C1
Biological Activity: COX-2/NLRP3-IN-1 (Compound 6k) is a COX-2/NLRP3 inhibitor with a IC50 of 1.53 μM for COX-2. COX-2/NLRP3-IN-1 exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway[1].
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COX-2/NLRP3-IN-1 | COX-2/NLRP3-IN-1 (Compound 6k) is a COX-2/NLRP3 inhibitor with a IC50 of 1.53 μM for COX-2. COX-2/NLRP3-IN-1 exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway. | |||||||||||||||||||||
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