3058626-26-6
3058626-26-6
Chemical Structure
Dyrk1A-IN-11
- CAS No.: 3058626-26-6
- Formula:C23H23F5N8O
- Molecular Weight:522.47
SMILES: CC1=NC2=C(N1CC(F)F)N=C(C3=C4N(N=C(N[C@@H]5CCN(C6COC6)CC5(F)F)N=C4)C=C3F)C=C2
Biological Activity: Dyrk1A-IN-11 (compound 166) is a potent dual-specificity tyrosine phosphorylation- regulated 1A (DYRK1A) inhibitor with an EC50 value of 0.0021 µM. Dyrk1A-IN-11 inhibits the Phospho-Tau (Thr212) with an EC50 value of 0.0361 µM[1].
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Dyrk1A-IN-11 | Dyrk1A-IN-11 (compound 166) is a potent dual-specificity tyrosine phosphorylation- regulated 1A (DYRK1A) inhibitor with an EC50 value of 0.0021 µM. Dyrk1A-IN-11 inhibits the Phospho-Tau (Thr212) with an EC50 value of 0.0361 µM. | |||||||||||||||||||||
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