3060585-94-3
3060585-94-3
Chemical Structure
NLRP3-IN-61
- CAS No.: 3060585-94-3
- Formula:C21H21N3O3
- Molecular Weight:363.41
InChIKey: ZLABDDXUINACGE-CYBMUJFWSA-N
SMILES: OC1=C(CCC2)C2=CC(C)=C1C3=CC=C(OC([C@@H]4CCC(NC4)=O)=N5)C5=N3
Biological Activity: NLRP3-IN-61 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-61 inhibits pyroptosis in THP-1 cell with an IC50 of 12.6 nM, inhibits IL-β release with an IC50 of 25.3 nM[1].
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NLRP3-IN-61 | NLRP3-IN-61 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-61 inhibits pyroptosis in THP-1 cell with an IC50 of 12.6 nM, inhibits IL-β release with an IC50 of 25.3 nM. | |||||||||||||||||||||
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