3061531-76-5
3061531-76-5
Chemical Structure
EGFR-IN-110
- CAS No.: 3061531-76-5
- Formula:C22H16ClFN4O2
- Molecular Weight:422.84
InChIKey: BFMJJIKPPAMPMX-UHFFFAOYSA-N
SMILES: C=CC1=NC=CC(OC2=CC3=C(NC4=CC=CC(Cl)=C4F)N=CN=C3C=C2OC)=C1
Biological Activity: EGFR-IN-110 (Compound 6) is a covalent EGFR inhibitor, with pIC50 values of 9.2 and 8.7 for EGFR enzyme and EGFR cell, respectively. EGFR-IN-110 shows high EGFR potency and good kinase selectivity[1].
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EGFR-IN-110 | EGFR-IN-110 (Compound 6) is a covalent EGFR inhibitor, with pIC50 values of 9.2 and 8.7 for EGFR enzyme and EGFR cell, respectively. EGFR-IN-110 shows high EGFR potency and good kinase selectivity. | |||||||||||||||||||||
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References
Keywords
