3064599-37-4
Chemical Structure
GSK4418959 (enantiomer)
Synonym(s): IDE275 (enantiomer)
- CAS No.: 3064599-37-4
- Formula:C31H30F4N4O5S
- Molecular Weight:646.65
IUPAC Name: (1S,2S,6R)-2-((2-fluoro-4-(trifluoromethyl)phenyl)carbamoyl)-6-(4-((N,1,2-trimethyl-1H-benzo[d]imidazole)-5-sulfonamido)phenyl)cyclohexane-1-carboxylic acid
InChIKey: CPNRNECAIBPHJF-LXWOLXCRSA-N
SMILES: O=S(C1=CC=C(N(C(C)=N2)C)C2=C1)(N(C3=CC=C([C@@H]4CCC[C@@H]([C@H]4C(O)=O)C(NC5=C(F)C=C(C(F)(F)F)C=C5)=O)C=C3)C)=O
Biological Activity: GSK4418959 enantiomer is an enantiomer of GSK4418959 (HY-169422). GSK4418959 (IDE275) is a non-covalent, reversible, selective and orally active WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner. GSK4418959 can be used for the study of microsatellite instability-high (MSI-H) cancer[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSK4418959 (enantiomer) | 95.0% | GSK4418959 enantiomer is an enantiomer of GSK4418959 (HY-169422). GSK4418959 (IDE275) is a non-covalent, reversible, selective and orally active WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner. GSK4418959 can be used for the study of microsatellite instability-high (MSI-H) cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
