3066823-45-5
3066823-45-5
Chemical Structure
WD6305
- CAS No.: 3066823-45-5
- Formula:C61H75F2N11O5S
- Molecular Weight:1112.38
InChIKey: FTIPAFFEWGMNDM-LZZSXEHKSA-N
SMILES: O=C(N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)CCC#CC(C=C4)=CC=C4CNC5=CC(N(CC6)CCC76NC(CN(C8=CC(F)=C(CN9CCC(C)(C)CC9)C=C8F)C7)=O)=NC=N5
Biological Activity: WD6305 is a potent and selective METTL3-METTL14 PROTAC degrader. WD6305 has DC50 values of 140 nM and 194 nM for METTL3 and METTL14, respectively. WD6305 inhibits m6A modification and proliferation of AML cells, and induces apoptosis.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WD6305 | 98.98% | WD6305 is a potent and selective METTL3-METTL14 PROTAC degrader. WD6305 has DC50 values of 140 nM and 194 nM for METTL3 and METTL14, respectively. WD6305 inhibits m6A modification and proliferation of AML cells, and induces apoptosis. | ||||||||||||||||||||
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Keywords
