3066836-42-5
3066836-42-5
Chemical Structure
CDK9 autophagic degrader 1
- CAS No.: 3066836-42-5
- Formula:C34H39N7O4S2
- Molecular Weight:673.85
SMILES: O=C(N1CC2=CC=CC=C2)N(CCCN3CCC(C(NC4=NC=C(SCC5=NC=C(C(C)(C)C)O5)S4)=O)CC3)C6=NC=CC=C6C1=O
Biological Activity: CDK9 autophagic degrader 1 (Compound 28) is a ATTEC degrader that can be used to degrade CDK9 and also affects the levels of the associated Cyclin T1. CDK9 autophagic degrader 1 shows over 80% CDK9 inhibition rate at 100 nM[1]. ( Pink: LC3B ligand (HY-168897); Black: linker (HY-W017758); Blue: target protein ligand (HY-10008); linker + target protein ligand (HY-168898))
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CDK9 autophagic degrader 1 | CDK9 autophagic degrader 1 (Compound 28) is a ATTEC degrader that can be used to degrade CDK9 and also affects the levels of the associated Cyclin T1. CDK9 autophagic degrader 1 shows over 80% CDK9 inhibition rate at 100 nM. ( Pink: LC3B ligand (HY-168897); Black: linker (HY-W017758); Blue: target protein ligand (HY-10008); linker + target protein ligand (HY-168898)) | |||||||||||||||||||||
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References
Keywords
