307345-51-3
307345-51-3
Chemical Structure
Sulphostin
- CAS No.: 307345-51-3
- Formula:C5H13N4O5PS
- Molecular Weight:272.22
InChIKey: AYVBXTCIPLYEBG-NMAPHRJESA-N
SMILES: [NH3+][C@@H]1C(N([P@](N)(NS(=O)([O-])=O)=O)CCC1)=O
Biological Activity: Sulphostin is a covalent inhibitor of dipeptidyl peptidase 4 (DPP4), dipeptidyl peptidase 9 (DPP9), and dipeptidyl peptidase 8 (DPP8) with IC50 values of 79, 1392, 6930 nM, respectively. Sulphostin causes phosphosulfamate modification, irreversibly inhibits the enzyme activity. Sulphostin can be used for inflammation and cancer study[1].
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Sulphostin | Sulphostin is a covalent inhibitor of dipeptidyl peptidase 4 (DPP4), dipeptidyl peptidase 9 (DPP9), and dipeptidyl peptidase 8 (DPP8) with IC50 values of 79, 1392, 6930 nM, respectively. Sulphostin causes phosphosulfamate modification, irreversibly inhibits the enzyme activity. Sulphostin can be used for inflammation and cancer study. | |||||||||||||||||||||
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References
Keywords
