3077464-19-5
Chemical Structure
PROTAC STAT6 degrader-14
- CAS No.: 3077464-19-5
- Formula:C47H53N11O5
- Molecular Weight:851.99
IUPAC Name: 6-(1-(3-(1H-1,2,3-triazol-1-yl)propanoyl)-1,2,5,6-tetrahydropyridin-3-yl)-4-(4-(4-(3-(1-(2,6-dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)propyl)piperazin-1-yl)phenyl)-N,N-dimethyl-1H-indole-2-carboxamide
InChIKey: MUYRSXAFAYCLGR-UHFFFAOYSA-N
SMILES: O=C(N(C)C)C1=CC2=C(C3=CC=C(N4CCN(CCCC5=CC=C6C(N(C)C(N6C7C(NC(CC7)=O)=O)=O)=C5)CC4)C=C3)C=C(C8=CCCN(C8)C(CCN9N=NC=C9)=O)C=C2N1
Biological Activity: PROTAC STAT6 degrader-14 is a bifunctional STAT6 PROTAC degrader with a DC50 of less than 1 nM. PROTAC STAT6 degrader-14 recruits STAT6 to an E3 ubiquitin ligase, promoting STAT6 ubiquitination and further inducing its degradation. STAT6 degrader-3 can be used in research related to inflammatory diseases and non-small cell lung cancer (NSCLC)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PROTAC STAT6 degrader-14 | 99.26% | PROTAC STAT6 degrader-14 is a bifunctional STAT6 PROTAC degrader with a DC50 of less than 1 nM. PROTAC STAT6 degrader-14 recruits STAT6 to an E3 ubiquitin ligase, promoting STAT6 ubiquitination and further inducing its degradation. STAT6 degrader-3 can be used in research related to inflammatory diseases and non-small cell lung cancer (NSCLC). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
