3079943-00-0
3079943-00-0
Chemical Structure
CC-M-1
- CAS No.: 3079943-00-0
- Formula:C28H29F2N9O4S
- Molecular Weight:625.65
InChIKey: ICLAEDCBZAYMBI-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=N1)C2=NN3C(C4=CN(N=N4)CCCN5CCCC(C5)O)=CN=C3C=C2)NS(=O)(C6=C(C=C(C=C6)F)F)=O
Biological Activity: CC-M-1 is a potent and selective PI3K/mTOR inhibitor. CC-M-1 inhibits PI3Kα/β/γ/δ and mTOR with IC50 values of 0.68, 1.02, 1.03, 8.03, and 15 nM, respectively. CC-M-1 inhibits the proliferation of colorectal cancer cell lines, including HCT-116 (IC50 = 0.38 μM) and HT-29 (IC50 = 1.70 μM). CC-M-1 can be used for colorectal cancer (CRC) research[1].
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CC-M-1 | CC-M-1 is a potent and selective PI3K/mTOR inhibitor. CC-M-1 inhibits PI3Kα/β/γ/δ and mTOR with IC50 values of 0.68, 1.02, 1.03, 8.03, and 15 nM, respectively. CC-M-1 inhibits the proliferation of colorectal cancer cell lines, including HCT-116 (IC50 = 0.38 μM) and HT-29 (IC50 = 1.70 μM). CC-M-1 can be used for colorectal cancer (CRC) research. | |||||||||||||||||||||
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References
Keywords
