3080792-24-8
Chemical Structure
TRG-192
- CAS No.: 3080792-24-8
- Formula:C24H20F6N8O2S2
- Molecular Weight:630.59
InChIKey: HTXVKNXKRKOYPP-UHFFFAOYSA-N
SMILES: O=C(NCC1=NC=CC(C(F)(F)F)=C1)C2=NN=C(CCCCC3=NN=C(C(NCC4=NC=CC(C(F)(F)F)=C4)=O)S3)S2
Biological Activity: TRG-192 is a potent and selective glutaminase (GLS) inhibitor with an IC50 of 68 nM. TRG-192 inhibits intracellular glutamate levels. TRG-192 is applicable to related research on non-small cell lung cancer[1].
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TRG-192 | TRG-192 is a potent and selective glutaminase (GLS) inhibitor with an IC50 of 68 nM. TRG-192 inhibits intracellular glutamate levels. TRG-192 is applicable to related research on non-small cell lung cancer. | |||||||||||||||||||||
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Keywords