3086360-36-0
3086360-36-0
Chemical Structure
SHP2-IN-46
- CAS No.: 3086360-36-0
- Formula:C17H19N5O
- Molecular Weight:309.37
InChIKey: USWGUGRVRGOHLZ-UHFFFAOYSA-N
SMILES: CC(C=C1NC2=CC=CC=C2C)=NN1C(N3)=NC(C)=C(C)C3=O
Biological Activity: SHP2-IN-46 is an orally active SHP2 inhibitor (IC50 = 11.76 μM). SHP2-IN-46 inhibits SHP2 enzymatic activity and mediates anti-tumor activity. SHP2-IN-46 suppresses cell proliferation in various cancer cells. SHP2-IN-46 can be used in research related to lung adenocarcinoma, pancreatic cancer and hepatoblastoma[1].
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SHP2-IN-46 | SHP2-IN-46 is an orally active SHP2 inhibitor (IC50 = 11.76 μM). SHP2-IN-46 inhibits SHP2 enzymatic activity and mediates anti-tumor activity. SHP2-IN-46 suppresses cell proliferation in various cancer cells. SHP2-IN-46 can be used in research related to lung adenocarcinoma, pancreatic cancer and hepatoblastoma. | |||||||||||||||||||||
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