3093413-09-0
3093413-09-0
Chemical Structure
GSPT2 degrader-1
- CAS No.: 3093413-09-0
- Formula:C29H32N4O6
- Molecular Weight:532.59
InChIKey: YNZYIANFUVBHKS-UHFFFAOYSA-N
SMILES: O=C1CCC(C(N1)=O)N2C(C3=CC=C(C=C3C2=O)C(NCCCCCCCCNC(C4=CC=CC=C4)=O)=O)=O
Biological Activity: GSPT2 degrader-1 (compound 619) is a selective molecular glue GSPT2 degrader targeting GSPT2. GSPT2 degrader-1 contains Thalidomide (HY-14658) and the linker of MDEG-541 (HY-150259). GSPT2 degrader-1 induces the degradation, but not GSPT1 or myelocytomatosis oncogene (MYC). GSPT2 degrader-1 can be used for research of gastrointestinal cancer[1].
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GSPT2 degrader-1 | GSPT2 degrader-1 (compound 619) is a selective molecular glue GSPT2 degrader targeting GSPT2. GSPT2 degrader-1 contains Thalidomide (HY-14658) and the linker of MDEG-541 (HY-150259). GSPT2 degrader-1 induces the degradation, but not GSPT1 or myelocytomatosis oncogene (MYC). GSPT2 degrader-1 can be used for research of gastrointestinal cancer. | |||||||||||||||||||||
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References
Keywords
