3093642-24-8
Chemical Structure
PROTAC EZH2 Degrader-43
- CAS No.: 3093642-24-8
- Formula:C61H76N12O8S
- Molecular Weight:1137.40
InChIKey: GUNMKYYHRNVGIV-QTMQUJPCSA-N
SMILES: CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)C(C5=CN(N=N5)CC(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=O)=O)=CC(C(NCC9=C(C=C(NC9=O)C)C)=O)=C2C
Biological Activity: PROTAC EZH2 Degrader-43 (compound 59) is a PROTAC protein degrader targeting EZH2 with an IC50 of 21.73 μM against SU-DHL-6 cells. PROTAC EZH2 Degrader-43 can be used for the research of lymphoma[1].
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PROTAC EZH2 Degrader-43 | PROTAC EZH2 Degrader-43 (compound 59) is a PROTAC protein degrader targeting EZH2 with an IC50 of 21.73 μM against SU-DHL-6 cells. PROTAC EZH2 Degrader-43 can be used for the research of lymphoma. | |||||||||||||||||||||
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Keywords