3099928-67-0
3099928-67-0
Chemical Structure
QXG-6442
- CAS No.: 3099928-67-0
- Formula:C21H17N5O4
- Molecular Weight:403.39
InChIKey: BRBLKCQDZREHRF-UHFFFAOYSA-N
SMILES: O=C(C1=CN2C=CC=CC2=N1)NC3=CC4=C(C(N(C4)C5CCC(NC5=O)=O)=O)C=C3
Biological Activity: QXG-6442 is a CK1α Molecular Glue Degrader. QXG-6442 exhibits CK1α degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. QXG-6442 induces antiproliferative effects in MOLM-14 cell line[1].
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QXG-6442 | 99.52% | QXG-6442 is a CK1α Molecular Glue Degrader. QXG-6442 exhibits CK1α degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. QXG-6442 induces antiproliferative effects in MOLM-14 cell line. | ||||||||||||||||||||
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References
Keywords
