3102-56-5
3102-56-5
Chemical Structure
DL-erythro-Dihydrosphingosine
- CAS No.: 3102-56-5
- Formula:C18H39NO2
- Molecular Weight:301.52
IUPAC Name: (2R,3S)-2-aminooctadecane-1,3-diol
InChIKey: OTKJDMGTUTTYMP-MSOLQXFVSA-N
SMILES: CCCCCCCCCCCCCCC[C@H](O)[C@H](N)CO
Biological Activity: DL-erythro-Dihydrosphingosine is a sphingosine-based PKC inhibitor. DL-erythro-Dihydrosphingosine directly inhibits the enzymatic activity of PLA2. DL-erythro-Dihydrosphingosine inhibits the activity of Bcl-2 protein involved in apoptosis. DL-erythro-Dihydrosphingosine inhibits the activity of matrix metalloproteinases (MMP). DL-erythro-Dihydrosphingosine is applicable for research on cancer and inflammatory diseases[1][2].
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DL-erythro-Dihydrosphingosine | 98.0% | DL-erythro-Dihydrosphingosine is a sphingosine-based PKC inhibitor. DL-erythro-Dihydrosphingosine directly inhibits the enzymatic activity of PLA2. DL-erythro-Dihydrosphingosine inhibits the activity of Bcl-2 protein involved in apoptosis. DL-erythro-Dihydrosphingosine inhibits the activity of matrix metalloproteinases (MMP). DL-erythro-Dihydrosphingosine is applicable for research on cancer and inflammatory diseases. | ||||||||||||||||||||
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References
- [1]. Chao R, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992;267(33):23459-23462. [Content Brief]
- [2]. Nakamura H, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004;484(1):9-17. [Content Brief]
