31059-54-8
31059-54-8
Chemical Structure
β-NETA
- CAS No.: 31059-54-8
- Formula:C16H20INO
- Molecular Weight:369.24
IUPAC Name: N,N,N-trimethyl-3-(naphthalen-2-yl)-3-oxopropan-1-aminium iodide
InChIKey: LIFHUGCXEAQKRZ-UHFFFAOYSA-M
SMILES: O=C(C1=CC=C2C=CC=CC2=C1)CC[N+](C)(C)C.[I-]
Biological Activity: β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 μM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM)[1][2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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β-NETA | 98.0% | β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 μM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM). | ||||||||||||||||||||
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References
- [1]. Sastry BV, et al. Relationships between chemical structure and inhibition of choline acetyltransferase by 2-(alpha-naphthoyl)ethyltrimethylammonium and related compounds. Pharmacol Res Commun. 1988 Sep;20(9):751-71. [Content Brief]
- [2]. B V Sastry, et al. 2-(alpha-Naphthoyl)ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase. J Pharmacol Exp Ther. 1988 Apr;245(1):72-80. [Content Brief]
Keywords
