3108075-72-2
3108075-72-2
Chemical Structure
KHK-IN-8
- CAS No.: 3108075-72-2
- Formula:C22H24F3N5O2
- Molecular Weight:447.45
InChIKey: OHVAMQAMWOAHLX-INIZCTEOSA-N
SMILES: CN([C@H]1CCN(C2=NC(NC3=CC(CCC(O)=O)=CC=C3)=C(C#N)C(C(F)(F)F)=C2)C1)C
Biological Activity: KHK-IN-8 is a selective KHK inhibitor, with an IC50 of 13.0 nM against hKHK-C and an IC50 of 22.7 nM against hKHK-A. KHK-IN-8 is applicable to research on non-alcoholic steatohepatitis, type 2 diabetes and obesity[1].
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KHK-IN-8 | KHK-IN-8 is a selective KHK inhibitor, with an IC50 of 13.0 nM against hKHK-C and an IC50 of 22.7 nM against hKHK-A. KHK-IN-8 is applicable to research on non-alcoholic steatohepatitis, type 2 diabetes and obesity. | |||||||||||||||||||||
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References
Keywords
