3108079-75-7
3108079-75-7
Chemical Structure
KEAP1-NRF2 PPI-IN-1
- CAS No.: 3108079-75-7
- Formula:C17H20ClN3O5S3
- Molecular Weight:478.01
InChIKey: XRAUKWUDYSUHJM-LLVKDONJSA-N
SMILES: ClC1=CC=CC=C1S(C2=C(N3CCN(C)C([C@H]3C)=O)SC(S(=O)(CC)=O)=N2)(=O)=O
Biological Activity: KEAP1-NRF2 PPI-IN-1 (compound 23) is an inhibitor targeting the KEAP1-NRF2 interaction. KEAP1-NRF2 PPI-IN-1 has IC50 values of 136 nM and 62 nM in the DNA damage assays of human TK6 and insect SF9 cell lines, respectively[1].
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KEAP1-NRF2 PPI-IN-1 | KEAP1-NRF2 PPI-IN-1 (compound 23) is an inhibitor targeting the KEAP1-NRF2 interaction. KEAP1-NRF2 PPI-IN-1 has IC50 values of 136 nM and 62 nM in the DNA damage assays of human TK6 and insect SF9 cell lines, respectively. | |||||||||||||||||||||
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