3108784-69-3
3108784-69-3
Chemical Structure
N-0920
- CAS No.: 3108784-69-3
- Formula:C31H38N8O6S
- Molecular Weight:650.75
InChIKey: YULXMMYEJYZEGC-HJOGWXRNSA-N
SMILES: O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(C2=NC=CS2)=O)=O)=O)OCC3=CC=CC=C3
Biological Activity: N-0920 is a potent TMPRSS2 inhibitor with an IC50 of 0.35 nM. N-0920 effectively inhibits SARS-CoV-2 variants EG.5.1 and JN.1 entry in Calu-3 cells, with picomolar EC50s values of 300 pM and 90 pM, respectively[1].
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N-0920 | N-0920 is a potent TMPRSS2 inhibitor with an IC50 of 0.35 nM. N-0920 effectively inhibits SARS-CoV-2 variants EG.5.1 and JN.1 entry in Calu-3 cells, with picomolar EC50s values of 300 pM and 90 pM, respectively. | |||||||||||||||||||||
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References
Keywords
