3109123-46-5
3109123-46-5
Chemical Structure
NB-3
- CAS No.: 3109123-46-5
- Formula:C11H14F3N3O
- Molecular Weight:261.24
InChIKey: NRMCGEBVBUWHHL-QMMMGPOBSA-N
SMILES: O=C(NCC(F)(F)F)N(C)[C@H](C1=CC=NC=C1)C
Biological Activity: NB-3 is a nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 inhibitor. NB-3 intercepts NAD hydrolysis and undergoes covalent conjugation with the reaction product adenosine diphosphate ribose (ADPR). The resulting small-molecule ADPR adducts are highly potent and confer compelling neuroprotection in neurological injury[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NB-3 | 99.89% | NB-3 is a nicotinamide adenine dinucleotide (NAD) hydrolase SARM1 inhibitor. NB-3 intercepts NAD hydrolysis and undergoes covalent conjugation with the reaction product adenosine diphosphate ribose (ADPR). The resulting small-molecule ADPR adducts are highly potent and confer compelling neuroprotection in neurological injury. | ||||||||||||||||||||
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References
Keywords
