3110559-06-0

HDAC6-IN-76 Chemical Structure
3110559-06-0

Chemical Structure

HDAC6-IN-76

  • CAS No.: 3110559-06-0
  • Formula:C24H32N2O7
  • Molecular Weight:460.52

InChIKey: BBKONKCEXPCYLJ-ZKOMFGNMSA-N

SMILES: C[C@@]12O[C@]3(O[C@@H]([C@@H]([C@]([H])(CC[C@H]([C@@H]4CC2)C)[C@@]34OO1)C)OCC5=CC=CC(/C=C/C(NO)=O)=N5)[H]

Biological Activity: HDAC6-IN-76 (Compound G25) is a selective HDAC6 inhibitor with an IC50 of 12 nM. HDAC6-IN-76 induces Autophagy in a p53-dependent manner. HDAC6-IN-76 induces Apoptosis in a p53-dependent manner. HDAC6-IN-76 exhibits anticancer activity against hematologic malignancies, including acute myeloid leukemia[1].

Cat. No. Product Name Purity Description Pricing
HY-181805 		HDAC6-IN-76 HDAC6-IN-76 (Compound G25) is a selective HDAC6 inhibitor with an IC50 of 12 nM. HDAC6-IN-76 induces Autophagy in a p53-dependent manner. HDAC6-IN-76 induces Apoptosis in a p53-dependent manner. HDAC6-IN-76 exhibits anticancer activity against hematologic malignancies, including acute myeloid leukemia.
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