3112754-10-3
3112754-10-3
Chemical Structure
Biguanide-4-(p-tolylethynyl)aniline
- CAS No.: 3112754-10-3
- Formula:C17H18N6
- Molecular Weight:306.37
InChIKey: FGFNDNGACAGDKF-UHFFFAOYSA-N
SMILES: N=C(NC(NCC1=CC=C(C=C1)C#CC2=CC=C(C=C2)N)=N)N
Biological Activity: Biguanide-4-(p-tolylethynyl) aniline is an amphiphilic cation and AMPK pathway phosphorylation inducer that crosses phospholipid membranes and accumulates in mitochondria, inhibiting pancreatic cancer cell proliferation by altering COXII and NDUFB8 protein levels. Biguanide-4-(p-tolylethynyl) aniline can be used in the study of pancreatic cancer[1].
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Biguanide-4-(p-tolylethynyl)aniline | Biguanide-4-(p-tolylethynyl) aniline is an amphiphilic cation and AMPK pathway phosphorylation inducer that crosses phospholipid membranes and accumulates in mitochondria, inhibiting pancreatic cancer cell proliferation by altering COXII and NDUFB8 protein levels. Biguanide-4-(p-tolylethynyl) aniline can be used in the study of pancreatic cancer. | |||||||||||||||||||||
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