3124554-07-7
Chemical Structure
Peptide CYP9
- CAS No.: 3124554-07-7
- Formula:C29H47N9O10
- Molecular Weight:681.74
InChIKey: SRJLRMCKKKIHJJ-SXVTUYLSSA-N
SMILES: O=C(N[C@@H](CCC(O)=O)C(NC1)=O)[C@@H](C(C)C)NC(CNC([C@H](CCCCN)NC(C[C@H](C(N)=O)NC([C@H](CCC2)N2C1=O)=O)=O)=O)=O
Biological Activity: Peptide CYP9 is a head-to-tail cyclic peptide derived from Antimicrobial peptide YD (HY-P11913). Peptide CYP9 inhibits the activation of the TGF-β/Smad signaling pathway, including the phosphorylation of Smad2/3. Peptide CYP9 inhibits the activation of the MAPK signaling pathway, including the phosphorylation of ERK and p38. Peptide CYP9 inhibits epithelial-mesenchymal transition. Peptide CYP9 inhibits extracellular matrix synthesis. Peptide CYP9 can be used for the research of pulmonary fibrosis[1].
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Peptide CYP9 | Peptide CYP9 is a head-to-tail cyclic peptide derived from Antimicrobial peptide YD (HY-P11913). Peptide CYP9 inhibits the activation of the TGF-β/Smad signaling pathway, including the phosphorylation of Smad2/3. Peptide CYP9 inhibits the activation of the MAPK signaling pathway, including the phosphorylation of ERK and p38. Peptide CYP9 inhibits epithelial-mesenchymal transition. Peptide CYP9 inhibits extracellular matrix synthesis. Peptide CYP9 can be used for the research of pulmonary fibrosis. | |||||||||||||||||||||
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