3128949-21-0
3128949-21-0
Chemical Structure
Stafori-2
- CAS No.: 3128949-21-0
- Formula:C11H10FO4PS
- Molecular Weight:288.23
InChIKey: JCRGEBGFCONISP-UHFFFAOYSA-N
SMILES: O=P(O)(OC1=C(F)C=C(C2=CSC(C)=C2)C=C1)O
Biological Activity: Stafori-2 is a selective STAT4 SH2 domain inhibitor. Stafori-2 binds to the STAT4 Src homology 2 (SH2) domain, blocking protein-protein interactions, with a human Ki value of 0.18 μM. Stafori-2 can be used in research related to autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and type 1 diabetes[1].
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Stafori-2 | Stafori-2 is a selective STAT4 SH2 domain inhibitor. Stafori-2 binds to the STAT4 Src homology 2 (SH2) domain, blocking protein-protein interactions, with a human Ki value of 0.18 μM. Stafori-2 can be used in research related to autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and type 1 diabetes. | |||||||||||||||||||||
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