313651-33-1
Chemical Structure
PD-0299685
- CAS No.: 313651-33-1
- Formula:C10H21NO2
- Molecular Weight:187.28
InChIKey: KKXFMWXZXDUYBF-BDAKNGLRSA-N
SMILES: CCC[C@@H](C)C[C@H](CN)CC(O)=O
Biological Activity: PD-0299685 is a potent Ca2+ channel α2δ ligand. PD-0299685 is promising for research of refractory genito-urinary pain and interstitial cystitis/bladder pain syndrome[1][2].
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PD-0299685 | PD-0299685 is a potent Ca2+ channel α2δ ligand. PD-0299685 is promising for research of refractory genito-urinary pain and interstitial cystitis/bladder pain syndrome. | |||||||||||||||||||||
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- [1]. Nickel JC, et al. Investigation of a Ca2+ channel α2δ ligand for the treatment of interstitial cystitis: results of a randomized, double-blind, placebo controlled phase II trial. J Urol. 2012 Sep;188(3):817-23.
- [2]. Nickel J C, et al. 821 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE IIA TRIAL OF A CA2+ CHANNEL α2Δ LIGAND, PD-0299685, FOR THE TREATMENT OF INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME[J]. The Journal of Urology, 2012, 187(4S): e335-e335.
Keywords