3136661-66-7
3136661-66-7
Chemical Structure
RSV-IN-15
- CAS No.: 3136661-66-7
- Formula:C25H25FN4O4
- Molecular Weight:464.49
InChIKey: UXKSFTVDXKDSPI-UHFFFAOYSA-N
SMILES: COC1=C(OC2CC2)C=CC(C(NNC(C3=CC(NCC)=CC(C4=CC=C(F)C=C4)=N3)=O)=O)=C1
Biological Activity: RSV-IN-15 is a selective inhibitor of the RSV RNA-dependent RNA polymerase PRNTase domain. RSV-IN-15 blocks polymerase-dependent RNA synthesis through allosteric binding. RSV-IN-15 exhibits antiviral EC50 = 37 nM against the RSV‑A Long strain in Hep‑2 cells, reduces polymerase-dependent reporter gene activity, and inhibits RSV RNA synthesis. RSV-IN-15 can be used for research on respiratory syncytial virus infection[1].
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RSV-IN-15 | RSV-IN-15 is a selective inhibitor of the RSV RNA-dependent RNA polymerase PRNTase domain. RSV-IN-15 blocks polymerase-dependent RNA synthesis through allosteric binding. RSV-IN-15 exhibits antiviral EC50 = 37 nM against the RSV‑A Long strain in Hep‑2 cells, reduces polymerase-dependent reporter gene activity, and inhibits RSV RNA synthesis. RSV-IN-15 can be used for research on respiratory syncytial virus infection. | |||||||||||||||||||||
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