3136748-24-5
3136748-24-5
Chemical Structure
TGF-8027
- CAS No.: 3136748-24-5
- Formula:C19H22N2O3
- Molecular Weight:326.39
InChIKey: YGVDYCKUVCKBFS-UHFFFAOYSA-N
SMILES: COC1=C(CCNC(C)C2=CC=CC=C2O)C=C(OC)C(C#N)=C1
Biological Activity: TGF-8027 is a selective 5-HT2A agonist that can cross the blood-brain barrier. TGF-8027 exhibits EC50s of 3.3 nM, 160 nM and 7600 nM against human 5-HT2A, 5-HT2C and 5-HT2B and exhibits EC50s against mouse 5-HT2A and mouse 5-HT2C of 14 and 210 nM. TGF-8027 can induce a head-shaking response in mice. TGF-8027 can be used to study diseases that target the 5-HT2A receptor (such as depression)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TGF-8027 | TGF-8027 is a selective 5-HT2A agonist that can cross the blood-brain barrier. TGF-8027 exhibits EC50s of 3.3 nM, 160 nM and 7600 nM against human 5-HT2A, 5-HT2C and 5-HT2B and exhibits EC50s against mouse 5-HT2A and mouse 5-HT2C of 14 and 210 nM. TGF-8027 can induce a head-shaking response in mice. TGF-8027 can be used to study diseases that target the 5-HT2A receptor (such as depression). | |||||||||||||||||||||
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