31828-68-9
31828-68-9
Chemical Structure
L-Homocysteine thiolactone hydrochloride
- CAS No.: 31828-68-9
- Formula:C4H8ClNOS
- Molecular Weight:153.63
IUPAC Name: (S)-3-aminodihydrothiophen-2(3H)-one hydrochloride
InChIKey: ZSEGSUBKDDEALH-DFWYDOINSA-N
SMILES: N[C@@H](CCS1)C1=O.Cl
Biological Activity: L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of Homocysteine. Homocysteine thiolactone hydrochloride prevents translational incorporation of homocysteine into proteins. L-Homocysteine thiolactone hydrochloride can induce elevated HHcy (hyperhomocysteinemia) in mice[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Homocysteine thiolactone hydrochloride | 99.99% | L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of Homocysteine. Homocysteine thiolactone hydrochloride prevents translational incorporation of homocysteine into proteins. L-Homocysteine thiolactone hydrochloride can induce elevated HHcy (hyperhomocysteinemia) in mice. | ||||||||||||||||||||
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References
- [1]. Jakubowski H, et al. Homocysteine thiolactone: metabolic origin and protein homocysteinylation in humans. J Nutr. 2000 Feb;130(2S Suppl):377S-381S. [Content Brief]
- [2]. Nehal M Elsherbiny, et al. Homocysteine Induces Inflammation in Retina and Brain. Biomolecules. 2020 Mar 3;10(3):393. [Content Brief]
- [3]. Ahmed S Ibrahim, et al. Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration. Oncotarget. 2016 Feb 23;7(8):8532-45. [Content Brief]
