321941-76-8
Chemical Structure
CLEC5A-IN-1
- CAS No.: 321941-76-8
- Formula:C21H27N3O9S2
- Molecular Weight:529.58
IUPAC Name: N2,N2,N7,N7-tetrakis(2-hydroxyethyl)-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide
InChIKey: MLFAYIJKXZKAMP-UHFFFAOYSA-N
SMILES: O=S(=O)(C1=CC=C2C=3C=CC(=CC3C(=NO)C2=C1)S(=O)(=O)N(CCO)CCO)N(CCO)CCO
Biological Activity: CLEC5A-IN-1 is an inhibitor that binds to CLEC5A, with a Kd value of 277 nM. CLEC5A-IN-1 inhibits HBV replication. CLEC5A-IN-1 induces the production of IFNα and IFNβ. CLEC5A-IN-1 reduces serum HBsAg and HBV DNA levels, as well as hepatic HBcAg levels, in HBV-infected animals. CLEC5A-IN-1 increases the positive rate and levels of serum HBsAb in HBV-infected animals. CLEC5A-IN-1 can be used for the research of hepatitis B[1].
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CLEC5A-IN-1 | CLEC5A-IN-1 is an inhibitor that binds to CLEC5A, with a Kd value of 277 nM. CLEC5A-IN-1 inhibits HBV replication. CLEC5A-IN-1 induces the production of IFNα and IFNβ. CLEC5A-IN-1 reduces serum HBsAg and HBV DNA levels, as well as hepatic HBcAg levels, in HBV-infected animals. CLEC5A-IN-1 increases the positive rate and levels of serum HBsAb in HBV-infected animals. CLEC5A-IN-1 can be used for the research of hepatitis B. | |||||||||||||||||||||
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