3237-44-3
3237-44-3
Chemical Structure
α-Isopropylmalate
Synonym(s): α-IPM
- CAS No.: 3237-44-3
- Formula:C7H12O5
- Molecular Weight:176.17
IUPAC Name: 2-hydroxy-2-isopropylsuccinic acid
InChIKey: BITYXLXUCSKTJS-UHFFFAOYSA-N
SMILES: O=C(CC(C(O)=O)(C(C)C)O)O
Biological Activity: α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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α-Isopropylmalate | 99.17% | α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast. | ||||||||||||||||||||
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α-Isopropylmalate (Standard) | ≥98% | α-Isopropylmalate (Standard) is the analytical standard of α-Isopropylmalate. This product is intended for research and analytical applications. α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast. | ||||||||||||||||||||
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2-Methylcitric acid (Standard) | ≥98% | 2-Methylcitric acid (Standard) is the analytical standard of 2-Methylcitric acid (HY-113371). This product is intended for research and analytical applications. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate. | ||||||||||||||||||||
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Pregabalin diacid | 98.47% | Pregabalin diacid is an impurity of Pregabalin, a lipophilic GABA (γ-aminobutyric acid) analog with anxiolytic and anticonvulsant activity. Pregabalin may act on the α(2)β subunit of voltage-dependent calcium channels, which are widely distributed in the peripheral and central nervous systems. Pregabalin can effectively induce hypoalgesia and improve behavioral disorders. | ||||||||||||||||||||
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Meglutol (Standard) | ≥98% | Meglutol (Standard) is the analytical standard of Meglutol. This product is intended for research and analytical applications. Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases. | ||||||||||||||||||||
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Hydroxycitric acid | 98.0% | Hydroxycitric acid is an orally active, multi-target, multi-bioactive organic acid. activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Hydroxycitric acid activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Hydroxycitric acid activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation. | ||||||||||||||||||||
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3-Hydroxy-2-methylglutaric acid | 3-Hydroxy-2-methylglutaric acid is a carboxylic acid metabolite. 3-Hydroxy-2-methylglutaric acid can be isolated from the flower Veronica incana L. 3-Hydroxy-2-methylglutaric acid can be used for upper respiratory tract diseases, malignant neoplasms, gastrointestinal tract and genitourinary system disorders and diabetes mellitus research. | |||||||||||||||||||||
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2-Hydroxy-2-(2-methylpropyl)butanedioic acid | 2-Hydroxy-2-(2-methylpropyl)butanedioic acid (compound 8) is a drug intermediate for synthesis of various active compounds. | |||||||||||||||||||||
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(2S)-2-Hydroxy-2-isopropylsuccinic acid | (2S)-2-Hydroxy-2-isopropylsuccinic acid (Ds-α-isopropylmalate) is an intermediate in the biosynthesis of Leucine. | |||||||||||||||||||||
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2,2-Dimethylsuccinic acid (Standard) | ≥98% | 2,2-Dimethylsuccinic acid (Standard) is the analytical standard of 2,2-Dimethylsuccinic acid. This product is intended for research and analytical applications. 2,2-Dimethylsuccinic acid belongs to the class of organic compounds known as methyl-branched fatty acids. | ||||||||||||||||||||
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2-Ethyl-2-methylsuccinic acid (Standard) | 99.70% | 2-Ethyl-2-methylsuccinic acid (Standard) is the analytical standard of 2-Ethyl-2-methylsuccinic acid. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Citramalic acid | 99.46% | Citramalic acid is an organic acid and soil phosphorus-solubilizing agent. Citramalic acid can be secreted by beet roots, and low phosphorus conditions promote its secretion. | ||||||||||||||||||||
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