α-Isopropylmalate
Based on 1 Customer Validation
α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast.
For research use only. We do not sell to patients.
- Purity: 99.17%
- CAS No.: 3237-44-3
- Formula: C7H12O5
- Molecular Weight:176.17
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 3237-44-3
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Appearance Solid
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Molecular Weight 176.17
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Formula C7H12O5
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Color White to off-white
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SMILES
O=C(CC(C(O)=O)(C(C)C)O)O
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Synonyms
α-IPM
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 250 mg/mL (1419.08 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Sze JY, et al. In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate. Science. 1992 Nov 13;258(5085):1143-5. [Content Brief]
[2]. Guo H, et al. Regulation of transcription in mammalian cells by yeast Leu3p and externally supplied inducer. FEBS Lett. 1996 Jul 22;390(2):191-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.6763 mL | 28.3817 mL | 56.7634 mL | 141.9084 mL |
| 5 mM | 1.1353 mL | 5.6763 mL | 11.3527 mL | 28.3817 mL | |
| 10 mM | 0.5676 mL | 2.8382 mL | 5.6763 mL | 14.1908 mL | |
| 15 mM | 0.3784 mL | 1.8921 mL | 3.7842 mL | 9.4606 mL | |
| 20 mM | 0.2838 mL | 1.4191 mL | 2.8382 mL | 7.0954 mL | |
| 25 mM | 0.2271 mL | 1.1353 mL | 2.2705 mL | 5.6763 mL | |
| 30 mM | 0.1892 mL | 0.9461 mL | 1.8921 mL | 4.7303 mL | |
| 40 mM | 0.1419 mL | 0.7095 mL | 1.4191 mL | 3.5477 mL | |
| 50 mM | 0.1135 mL | 0.5676 mL | 1.1353 mL | 2.8382 mL | |
| 60 mM | 0.0946 mL | 0.4730 mL | 0.9461 mL | 2.3651 mL | |
| 80 mM | 0.0710 mL | 0.3548 mL | 0.7095 mL | 1.7739 mL | |
| 100 mM | 0.0568 mL | 0.2838 mL | 0.5676 mL | 1.4191 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
α-Isopropylmalate Related Classifications
HY-N9960 Related Classifications
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