3251-69-2
3251-69-2
Chemical Structure
Imidazoleacetic acid hydrochloride
Synonym(s): Imidazolyl-4-acetic acid hydrochloride
- CAS No.: 3251-69-2
- Formula:C5H7ClN2O2
- Molecular Weight:162.58
IUPAC Name: 2-(1H-imidazol-5-yl)acetic acid hydrochloride
InChIKey: MWHLCFYPFGFBQO-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CN=CN1.[H]Cl
Biological Activity: Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain[1][2][3].
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Imidazoleacetic acid hydrochloride | 99.94% | Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain. | ||||||||||||||||||||
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Imidazoleacetic acid hydrochloride (Standard) | ≥98% | Imidazoleacetic acid (hydrochloride) (Standard) is the analytical standard of Imidazoleacetic acid (hydrochloride). This product is intended for research and analytical applications. Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain. | ||||||||||||||||||||
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References
- [1]. Prell GD, et al. Imidazoleacetic acid-ribotide: an endogenous ligand that stimulates imidazol(in)e receptors. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13677-82. [Content Brief]
- [2]. Clifford JM, et al. Biochemical and pharmacological actions of imidazoleacetic acid. Biochem Pharmacol. 1973 Feb 15;22(4):535-42. [Content Brief]
- [3]. Thomas B, et al. Imidazoleacetic acid, a gamma-aminobutyric acid receptor agonist, can be formed in rat brain by oxidation of histamine. J Neurochem. 1995 Aug;65(2):818-26. [Content Brief]
