325795-25-3
Chemical Structure
BB-83698
- CAS No.: 325795-25-3
- Formula:C28H42N4O6
- Molecular Weight:530.66
IUPAC Name: (R)-N-((S)-1-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3-cyclopentyl-2-((N-hydroxyformamido)methyl)propanamide
InChIKey: IBEANEPZNLVRRY-RCZVLFRGSA-N
SMILES: O=C([C@H](C(C)(C)C)NC([C@@H](CN(O)C=O)CC1CCCC1)=O)N2CCN(CC2)CC3=CC=C4C(OCO4)=C3
Biological Activity: BB-83698 is a peptide deformylase (PDF) inhibitor. BB-83698 exhibits potent in vitro activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) range of 0.06-0.25μg/mL. BB-83698 elevates the survival rate of mice regardless of whether the infecting strain carries resistance mechanisms. BB-83698 can be used for the study of diseases related to drug-resistant Streptococcus pneumoniae infections[1].
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BB-83698 | BB-83698 is a peptide deformylase (PDF) inhibitor. BB-83698 exhibits potent in vitro activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) range of 0.06-0.25μg/mL. BB-83698 elevates the survival rate of mice regardless of whether the infecting strain carries resistance mechanisms. BB-83698 can be used for the study of diseases related to drug-resistant Streptococcus pneumoniae infections. | |||||||||||||||||||||
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Keywords
