327031-30-1
327031-30-1
Chemical Structure
LY2023-001
- CAS. Nr.: 327031-30-1
- Formula:C19H18N6O3
- Molecular Weight:378.38
InChIKey: BYPLIXDRZKQFEX-AWQFTUOYSA-N
SMILES: COC1=C(O)C(OC)=CC(/C=N/NC2=NN=C(C(C=C(C)C=C3)=C3N4)C4=N2)=C1
Biological Activity: LY2023-001 is a potent G2019S LRRK2 inhibitor with an IC50 of 12.9 nM. LY2023-001 formed stable hydrogen bonds with Glu1948, and Ala1950 in the G2019S LRRK2 protein[1].
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LY2023-001 | LY2023-001 is a potent G2019S LRRK2 inhibitor with an IC50 of 12.9 nM. LY2023-001 formed stable hydrogen bonds with Glu1948, and Ala1950 in the G2019S LRRK2 protein. | |||||||||||||||||||||
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