329716-61-2
Chemical Structure
J-115814
- CAS No.: 329716-61-2
- Formula:C29H38ClN5O3S
- Molecular Weight:572.16
IUPAC Name: isopropyl (3-chloro-5-(1-((6-(2-(5-ethyl-4-methylthiazol-2-yl)ethyl)-4-morpholinopyridin-2-yl)amino)ethyl)phenyl)carbamate
InChIKey: AZGZXUZMWKHDDH-UHFFFAOYSA-N
SMILES: CC1=C(SC(CCC2=CC(N3CCOCC3)=CC(NC(C)C4=CC(NC(OC(C)C)=O)=CC(Cl)=C4)=N2)=N1)CC
Biological Activity: J-115814 is a potent and selective neuropeptide Y1 antagonist with Ki values of 1.4, 1.8, 1.9, >10000, 620, 6000, >10000 nM for hY1, rY1, mY1, hY2, hY4, hY5, mY6, respectively. J-115814 inhibits feeding behaviors[1].
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J-115814 | J-115814 is a potent and selective neuropeptide Y1 antagonist with Ki values of 1.4, 1.8, 1.9, >10000, 620, 6000, >10000 nM for hY1, rY1, mY1, hY2, hY4, hY5, mY6, respectively. J-115814 inhibits feeding behaviors. | |||||||||||||||||||||
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Keywords