331662-51-2
331662-51-2
Chemical Structure
LDDN-0003499
- CAS No.: 331662-51-2
- Formula:C16H13Cl2N3O2
- Molecular Weight:350.20
IUPAC Name: N-(2,4-dichlorophenyl)-6,7-dimethoxyquinazolin-4-amine
InChIKey: PKEYRKYHSXFGBA-UHFFFAOYSA-N
SMILES: ClC1=CC=C(NC=2N=CN=C3C=C(OC)C(OC)=CC32)C(Cl)=C1
Biological Activity: LDDN-0003499 is a Src family tyrosine kinase inhibitor and anti-inflammatory agent. LDDN-0003499 reduces basal and Aβ-stimulated levels of active, phosphorylated Lyn and Src kinases, and attenuates Aβ-stimulated secretion of pro-inflammatory cytokines TNFα and IL-6 in microglial cells. LDDN-0003499 can be used for the research of Alzheimer's disease[1].
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LDDN-0003499 | LDDN-0003499 is a Src family tyrosine kinase inhibitor and anti-inflammatory agent. LDDN-0003499 reduces basal and Aβ-stimulated levels of active, phosphorylated Lyn and Src kinases, and attenuates Aβ-stimulated secretion of pro-inflammatory cytokines TNFα and IL-6 in microglial cells. LDDN-0003499 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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