33403-37-1
Chemical Structure
Nornidulin
- CAS No.: 33403-37-1
- Formula:C19H15Cl3O5
- Molecular Weight:429.68
IUPAC Name: (Z)-6-(but-2-en-2-yl)-2,4,7-trichloro-3,8-dihydroxy-1,9-dimethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one
InChIKey: XEQDVQKKHOQZEP-WAYWQWQTSA-N
SMILES: CC1=C(C(Cl)=C(C2=C1OC(C3=C(O2)C(Cl)=C(C(Cl)=C3C)O)=O)/C(C)=C\C)O
Biological Activity: Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC=2 μg/mL).2 Nornidulin has cytotoxic activity in MOLT-3 cells (IC50=35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s=>116.4 μM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nornidulin | 99.3% | Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC=2 μg/mL).2 Nornidulin has cytotoxic activity in MOLT-3 cells (IC50=35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s=>116.4 μM). | ||||||||||||||||||||
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Keywords
