335381-68-5
Chemical Structure
KR-31378
- CAS No.: 335381-68-5
- Formula:C22H27N5O4
- Molecular Weight:425.48
InChIKey: OZHUPJHJQIEDFA-DXIQSLLYSA-N
SMILES: N#CN/C(NCC1=CC=CC=C1)=N\[C@@H]2C3=CC(N)=CC=C3O[C@@](C)([C@H]2O)C(OC)OC
Biological Activity: KR-31378 is a neuroprotectant with dose-dependent pharmacokinetic properties and relevant activity in rats. After intravenous and oral administration of KR-31378 in rats, its pharmacokinetic parameters showed dose-dependent changes, such as decreased clearance with increasing doses, good oral absorption, and comparable AUCs for intravenous and oral administration at different doses.
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KR-31378 | KR-31378 is a neuroprotectant with dose-dependent pharmacokinetic properties and relevant activity in rats. After intravenous and oral administration of KR-31378 in rats, its pharmacokinetic parameters showed dose-dependent changes, such as decreased clearance with increasing doses, good oral absorption, and comparable AUCs for intravenous and oral administration at different doses. | |||||||||||||||||||||
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Keywords
