3367-88-2
Chemical Structure
(E/Z)-GSK-3β inhibitor 1
- CAS No.: 3367-88-2
- Formula:C14H10N2O
- Molecular Weight:222.24
IUPAC Name: (Z)-3-(pyridin-2-ylmethylene)indolin-2-one
InChIKey: YKQONSWBHGBDSB-XFXZXTDPSA-N
SMILES: O=C1NC2=C(C=CC=C2)/C1=C/C3=NC=CC=C3
Biological Activity: (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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(E/Z)-GSK-3β inhibitor 1 | 99.10% | (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM. | ||||||||||||||||||||
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Keywords