3367-88-2

(E/Z)-GSK-3β inhibitor 1 Chemical Structure
3367-88-2

Chemical Structure

(E/Z)-GSK-3β inhibitor 1

  • CAS No.: 3367-88-2
  • Formula:C14H10N2O
  • Molecular Weight:222.24

IUPAC Name: (Z)-3-(pyridin-2-ylmethylene)indolin-2-one

InChIKey: YKQONSWBHGBDSB-XFXZXTDPSA-N

SMILES: O=C1NC2=C(C=CC=C2)/C1=C/C3=NC=CC=C3

Biological Activity: (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].

Cat. No. 상품명 Purity 제품 설명 Pricing
HY-126144A
(E/Z)-GSK-3β inhibitor 1 99.10% (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM.
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