34627-62-8
34627-62-8
Chemical Structure
3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine
- CAS No.: 34627-62-8
- Formula:C29H27ClN2O4
- Molecular Weight:502.99
IUPAC Name: 1-((2R,4R,5R)-4-chloro-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: UPBVZHGDVFKZMX-TWJOJJKGSA-N
SMILES: Cl[C@@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5
Biological Activity: 3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine | 3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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