35094-46-3
35094-46-3
Chemical Structure
Adenosine 5'-O-(3-thiotriphosphate)
Synonym(s): ATPγS
- CAS No.: 35094-46-3
- Formula:C10H16N5O12P3S
- Molecular Weight:523.25
InChIKey: NLTUCYMLOPLUHL-KQYNXXCUSA-N
SMILES: NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(O)(OP(O)(OP(S)(O)=O)=O)=O)O3
Biological Activity: Adenosine 5'-O-(3-thiotriphosphate) (ATPγS) is an ATP analog. Adenosine 5'-O-(3-thiotriphosphate) can serve as a phosphate donor for Abl tyrosine kinase and ERK2[1][2].
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Adenosine 5'-O-(3-thiotriphosphate) | Adenosine 5'-O-(3-thiotriphosphate) (ATPγS) is an ATP analog. Adenosine 5'-O-(3-thiotriphosphate) can serve as a phosphate donor for Abl tyrosine kinase and ERK2. | |||||||||||||||||||||
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References
- [1]. Kinoshita E, et al. Profiling of protein thiophosphorylation by Phos-tag affinity electrophoresis: evaluation of adenosine 5'-O-(3-thiotriphosphate) as a phosphoryl donor in protein kinase reactions. Proteomics. 2014 Mar;14(6):668-79.
- [2]. Gille A, et al. Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates. Biochemical pharmacology. 2005 Dec 19;71(1-2):89-97.
