352653-12-4
Chemical Structure
VT5
- CAS No.: 352653-12-4
- Formula:C113H190N30O40
- Molecular Weight:2608.89
SMILES: O=C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CC(O)=O)C(N2[C@@H](CCC2)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CCCCN)C(NCC(N[C@@H](CC(O)=O)C(N3[C@@H](CCC3)C(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
Biological Activity: VT5 is a β-sheet amphipathic peptide consisting of 26 amino acids. VT5 has the ability to form β-sheets for cellular internalization[1][2].
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VT5 | VT5 is a β-sheet amphipathic peptide consisting of 26 amino acids. VT5 has the ability to form β-sheets for cellular internalization. | |||||||||||||||||||||
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References
- [1]. Singh T, et al. Versatility of cell-penetrating peptides for intracellular delivery of siRNA. Drug Deliv. 2018 Nov;25(1):1996-2006. [Content Brief]
- [2]. Krause E, et al. Conformation of a water-soluble beta-sheet model peptide. A circular dichroism and Fourier-transform infrared spectroscopic study of double D-amino acid replacements. Int J Pept Protein Res. 1996 Dec;48(6):559-68. [Content Brief]
